Microcrystalline Cellulose USP/NF, EP, JP

Avicel PH, IFF’s innovator brand of microcrystalline cellulose, is a purified, partially depolymerized alpha-cellulose manufactured by acid hydrolysis of specialty wood pulp. The process of polymerization involves high levels of quality and stringency.

Avicel PH’s unique properties – superior compactibility, drug carrying capacity and rapid disintegration make it the excipient of choice in direct compression applications. When used in the wet granulation process, the risk of over-granulation is reduced, screen blockage is avoided and uniform, rapid drying is promoted. The distinct properties of this excipient also benefit the dry granulation processes of roller compaction and slugging. Avicel PH is an excellent extrusion-spheronization binder and its inclusion in capsule formulations improves flow, facilitates plug formation and aids capsule disintegration.

With the development of differentiated grades, Avicel PH remains an indispensable formulation tool, boosting productivity and meeting tough formulation challenges.