Silicified Microcrystalline Cellulose USP/NF and Microcrystalline Cellulose USP/NF, EP, JP and Colloidal Silicon Dioxide USP/NF, EP, JP

Avicel SMCC, a high functionality co-processed spray-dried excipient comprising of 98 percent of microcrystalline cellulose (MCC) and 2 percent of colloidal silicon dioxide. Silicification reduces cohesiveness of the powder blend thus enhancing flow properties compared to MCC. It increases the surface area, which improves the binding properties of MCC. It also results in better compactibility, provides excellent homogeneity and content uniformity even for low-dosed, micronized active ingredients.