Sol International Private Limited

CELPHERE

Brand of

Microcrystalline Cellulose Spheres USP/NF, EP, JPE

Celphere is a 100 percent microcrystalline cellulose sphere which is highly spherical and uniform in its particle size distribution, enabling greater accuracy and consistency in drug layering and coating.

This product exhibits high mechanical strength and low friability, allowing it to withstand the rigors of fluidized-bed or Wurster coating process. Celphere is insoluble, yet it absorbs water during processing, thereby reducing particle agglomeration even at high spray rates. During dissolution it avoids film deformation or rupturing under stress. It has low chemical reactivity and hence can be freely used to layer high dose, moisture sensitive and potent actives.

Apparent Viscosity (2%, cP) Applications
106-212 Used as a spherical seed core for drug layering, film coating and for manufacturing of sustained release or taste masked granules
150 - 300 Used as a spherical seed core for drug layering, film coating and for manufacturing of sustained release or taste masked granules
300 - 500 Used as a spherical seed core for drug layering, film coating and for manufacturing of sustained release or taste masked granules
500 - 710 Used as a spherical seed core for drug layering, film coating and for manufacturing of sustained release or taste masked granules
710 - 850 Used as a spherical seed core for drug layering, film coating and for manufacturing of sustained release or taste masked granules

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