Microcrystalline Cellulose Spheres USP/NF, EP, JPE
Celphere is a 100 percent microcrystalline cellulose sphere which is highly spherical and uniform in its particle size distribution, enabling greater accuracy and consistency in drug layering and coating.
This product exhibits high mechanical strength and low friability, allowing it to withstand the rigors of fluidized-bed or Wurster coating process. Celphere is insoluble, yet it absorbs water during processing, thereby reducing particle agglomeration even at high spray rates. During dissolution it avoids film deformation or rupturing under stress. It has low chemical reactivity and hence can be freely used to layer high dose, moisture sensitive and potent actives.