Sol International Private Limited

D 161

Brand of

HIGH PURITY, LOW ENDOTOXIN EXCIPIENTS

Evonik’s cQrex® portfolio is specifically designed to enhance cell culture media and optimize bioprocessing with ingredients that meet stringent regulatory requirements for biopharmaceutical manufacturing. Unlike free L-glutamine, L-tyrosine and L-cysteine, cQrex® peptides are resistant to degradation and highly soluble in media at neutral pH. The antioxidant cQrex® AKG limits oxidative damages in the cell.

Formulating or supplementing media with cQrex® peptides allows for process intensification and simplification with concentrated media and single-feed systems. They enable productivity increase and production cost savings, ensuring highly efficient manufacturing of biopharmaceuticals.

Pharmacopeial Names Applications
Sucrose, low endotoxin, USP/NF, EP, JP, ChP, Beet derived As carrying agents and lyoprotectants in parenteral formulations, particularly intravenous and intramuscular injectables For blood protein fractionation products Also used in biopharmaceutical applications as protein stabilizers, bioprocessing components and supplements
Sucrose, low endotoxin, USP/NF, EP, JP, ChP, Cane derived As carrying agents and lyoprotectants in parenteral formulations, particularly intravenous and intramuscular injectables For blood protein fractionation products Also used in biopharmaceutical applications as protein stabilizers, bioprocessing components and supplements
Trehalose Dihydrate, low endotoxin, USP/NF, EP, JP, ChP  As carrying agents and lyoprotectants in parenteral formulations, particularly intravenous and intramuscular injectables For blood protein fractionation products Also used in biopharmaceutical applications as protein stabilizers, bioprocessing components and supplements
Maltose hydrate, low endotoxin USP/NF As carrying agents and lyoprotectants in parenteral formulations, particularly intravenous and intramuscular injectables For blood protein fractionation products Also used in biopharmaceutical applications as protein stabilizers, bioprocessing components and supplements
Sodium succinate hexahydrate, low endotoxin, USP/NF Biopharmaceutical ingredient for pH buffering and final product formulation (e.g. Antibody Drug Conjugates)
Tris base, low endotoxin, USP/NF, EP, JP, ChP, Biopharmaceutical ingredient for pH buffering and final product formulation (e.g. Antibody Drug Conjugates)
Tris HCl, low endotoxin Biopharmaceutical ingredient for pH buffering and final product formulation (e.g. Antibody Drug Conjugates)
D-Galactose, low endotoxin, EP Used in biopharmaceutical applications as a key component to ensure consistency of therapeutic glycosylation, potency, and yield
D-Mannose Cell culture media additive to which serves as an energy source, precursor for synthesis of proteins, maintains osmotic balance and functions in cell signaling

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