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KOLLIDON CL

Brand of

Crospovidone USP/NF, EP, JP

The insoluble grades of Kollidon are crosslinked polyvinylpyrrolidone manufactured by a polymerization process using an aqueous system, yielding crosslinked insoluble PVP in the form of a ‘popcorn’ polymer.

Kollidon CL grades are used as ‘superdisintegrants’ due to their property to swell very fast and predictably without forming a gel. These grades accelerate dissolution and bioavailability due to their power to form complexes with many insoluble actives.
Particle Size Distributions Applications
> 50μm: max. 80% Standard grade, for use as a tablet disintegrant and for improving the release of active substances from tablets, capsules and granules
> 50μm: max. 60% Fine particle size grade, for use as a disintegrant in tablets, especially in formulations for small tablets and in wet granulation
> 50μm: max. 30% Super-fine particle size grade for use as a disintegrant in fast dispersible tablets due to its smooth mouth feel
< 15μm: min. 90% Micronized particle size grade used as a stabilizer for oral and topical suspensions and for improving the release of active substances from tablets, capsules and granules

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